Rivista di formazione e aggiornamento di pediatri e medici operanti sul territorio e in ospedale. Fondata nel 1982, in collaborazione con l'Associazione Culturale Pediatri

Gli articoli più visti nel 2021

1) Consensus - Febbraio 2021

Gestione del Covid-19 in età pediatrica: documento di consenso

Gruppo di Lavoro su Covid-19 in Pediatria della Regione Emilia-Romagna (RE-CO-PED)
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has rapidly spread, becoming the first pandemic of the 21st century by death toll. Children appear to be less affected than adults, with a milder clinical presentation and a significantly lower mortality rate. However, serious complica-tions can occur in childhood, such as COVID-19 temporally related multisystem inflammatory syn-drome (MIS-C). Some aspects of SARS-CoV-2 infection in children and adolescents remain un-clear and the optimal treatment has not been defined. The Working Group on COVID-19 in Paediatrics of the Emilia-Romagna Region (RE-CO-PED) has produced a consensus document with practical recommendations based on a systematic review of the literature and on the clinical experi-ence of the expert group. Evidence is reported regarding prevention measures, diagnostic tools as well as home and hospital therapeutic management of complicated cases (MIS-C). The educational and psychological effects of the pandemic in the paediatric and adolescent age are reported, with the need to define coordinated interventions (between paediatricians, neurospychiatrists, psycholo-gists and educational services) for the prevention and treatment of documented emotional, relational and educational consequences caused by the lockdown, school closures and social distances.

disponibile pdf 933 kB

2) Linee guida - Ottobre 2020

La prima infezione urinaria febbrile in bambini di età compresa tra 2 mesi e 3 anni

Gruppo di lavoro sulle infezioni delle vie urinarie della Società Italiana di Nefrologia Pediatrica (SINePe)
The aim was to update the recommendations for the diagnosis, treatment and follow-up of the first febrile urinary tract infection in young children, which were first published in 2012 and endorsed by the Italian Society of Paediatric Nephrology. The Italian recommendations were revised on the basis of a review of the literature published from 2012 to October 2018. An ad hoc evaluation of the risk factors, which were published in the previous recommendations, was carried out to identify children with high-grade vesicoureteral reflux or renal scarring. When evidence was not available, the working group held extensive discussions during various meetings and through email exchanges. Four major modifications have been introduced. The method for collecting urine for culture and its interpretation has been re-evaluated. The algorithm that guides clinical decisions to proceed with voiding cystourethrography has been reformulated. The suggested antibiotics have been revised and further restrictions of the use of antibiotic prophylaxis have been recommended. These updated recommendations have now been endorsed by the Italian Society of Paediatric Nephrology and the Italian Society for Paediatric Infectivology. They can also be used to compare other available recommendations, as a worldwide consensus in this area is still lacking.

non disponibile pdf 191 kB

3) Editoriali - Giugno 2021


Pession A

disponibile pdf 122 kB

4) Linee guida - Giugno 2015

Le nuove Linee Guida sulla bronchiolite

G. Cozzi, S. Pusceddu, L. Mambelli, E. Barbi, F. Marchetti
Bronchiolitis is the leading cause of lower respiratory tract infection and hospitalization in children less than 1 year old. The American Academy of Pediatrics (AAP) and the Italian Pediatric Society (SIP) have recently published new guidelines for the diagnosis, management and prevention of bronchiolitis. Indications in the two documents are similar, but bronchiolitis management is still debated. In particular pharmacological treatments are not supported by enough evidence, whereas support therapy with oxygen, hydration and nutrition seems the only useful option. The aim of the present work is to summarise these new guidelines, adding a brief comment to each recommendation, in order to produce a useful and practical everyday guide for the paediatrician.

disponibile pdf 321 kB

5) Speciale - Luglio 2021


Marchetti F, Barbi E

non disponibile pdf 539 kB

6) ABC - Febbraio 2004

Leggere l’emocromo

I. Bruno

non disponibile pdf 213 kB

7) L'angolo dell'immunologo - Ottobre 2001

Quando sospettare un’immunodeficienza

A. Tommasini, A. Insalaco, C. Perez, A.R. Soresina, A. Plebani

disponibile pdf 71 kB

8) Vaccinare - Dicembre 2021

La vaccinazione per il Covid-19 in bambini di età compresa tra i 5 e gli 11 anni

Documento approvato dalle Società e Associazioni pediatriche italiane

disponibile pdf 348 kB

10) Aggiornamento - Marzo 2021

Decifrare la bassa statura nei bambini

Chiarelli F, Castorani V, Polidori N
Short stature is the most common cause of referral to paediatricians. Only a minority of children with short stature have an underlying pathology. Although well-established diagnostic and management paradigms do exist, recent advances in molecular technologies have significantly improved our understanding of the genetic causes of short stature. Therefore, after the exclusion of nutritional, hormonal, inflammatory or systemic disorders, or skeletal dysplasias and syndromes, genetic causes should be ever supposed and genetic evaluation considered. An appropriate diagnosis of short stature should be performed as early as possible and personalized treatment should be started in a timely manner. Novel treatment approaches have been also proposed both as diagnostic tools and as therapeutic agents to optimize the approach to short stature. Therefore, detailed characterization of children with poor growth is necessary to perform a tailored diagnostic and therapeutic workup with the aim to decipher the causes of short stature better.

non disponibile pdf 200 kB

11) Editoriali - Aprile 2021

Bambini che (non) vanno a scuola: prima e dopo il Covid

Abbracciavento G

disponibile pdf 52 kB

12) Vaccinare - Marzo 2021

Vaccini Covid-19: disponibilità ed efficacia

Davanzo R
The Covid-19 vaccination campaign represents a challenge for the health system. Eight Covid-19 vaccines belonging to 4 different categories of technology are currently available. More than the specific type of selected vaccine, major influencing factors for the success of the vaccination campaign are a quick coverage of the population, including the paediatric one, and the surveillance regarding the new viral variants.

disponibile pdf 76 kB

13) Speciale - Luglio 2021

Asma e allergologia

Longo G, Badina L

non disponibile pdf 837 kB

14) Aggiornamento - Aprile 2021

Le sindromi autoinfiammatorie: quando non è solo PFAPA

Tommasini A, Lepore L
PFAPA (Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis) is the most common self-inflammatory disorder in children. The diagnosis of PFAPA is easy, based on Thomas criteria, and the prognosis is good. Differential diagnosis with hereditary periodic fever syndromes (Familial Mediterranean Fever, Mevalonate Kinase Deficiency, TRAPS and CAPS) should be considered only in the presence of red flags such as early onset, severe abdominal complaints, arthritis and severe rashes. Some patients may present distinct clinical entities with periodic fevers that neither meet PFAPA criteria nor hereditary periodic fever syndromes genotypes. Subjects with these “Undifferentiated Periodic Fever” may respond to glucocorticoids or colchicines or to anakinra in the most severe cases and still have an undetermined prognosis.

non disponibile pdf 434 kB

15) Linee guida - Giugno 2021

Ingestione di corpi estranei e di caustici nei bambini

Bramuzzo M, Oliva S a nome del Gruppo di Lavoro SIGENP e AIGO
Foreign bodies or caustic ingestion is a frequent occurrence in children and can result in significant morbidity. Managing these conditions requires different levels of experience and expertise. An en-doscopy is often necessary but an incorrect use of this procedure is common. Indications and timing of endoscopy mainly depends on the clinical conditions of the child, the type of object and its posi-tion or the type of substance. The Italian Society of Gastroenterology, Hepatology and Pediatric Nutrition (SIGENP) together with the Italian Association of Gastroenterologists and Hospital En-doscopists (AIGO) has produced the first Italian guidelines for the management of the ingestion of foreign and caustic bodies in children.

non disponibile pdf 843 kB

16) Consensus - Novembre 2019

La sindrome nefrosica in età pediatrica

Consensus della Società Italiana di Nefrologia Pediatrica (SINePe)
In Italy are not guidelines for the management of idiopathic nephrotic syndrome (NS) in paediatric age. The choice of a treatment with steroids has always been based on the clinical experience of each centre. The present Consensus of the Italian Paediatric Nephrology Association, updated as an overview of the literature in August 2015, aims to provide a multidisciplinary review on the diagnosis and treatment of NS at the onset by proposing a shared therapeutic protocol for both hospital and family paediatricians. The Consensus gives recommendations on the early recognition and treatment of complications (oedema, hypovolemia, infections and thromboembolic events) as well as on the definition of cortico-resistance and indications on the performance of kidney biopsy.

non disponibile pdf 190 kB

18) Speciale - Luglio 2021


Berti I, Cutrone M

non disponibile pdf 663 kB

19) Aggiornamento monografico - Maggio 2005

Sindrome adreno-genitale congenita da deficit di 21-idrossilasi

A. Balsamo, A. Cicognani
Congenital adrenal hyperplasia (CAH) refers to a group of inherited disorders of adrenal steroidogenesis. More than 90% of CAH is due to 21-hydroxylase deficiency (21-OH-D), found in 1:10.000 to 1:15.000 live births as classical form and detected in about 2:100 of certain populations as non classical form. Females with classical 21-OH-D present at birth genital virilization. Potentially life-threatening adrenal crisis may characterize two-third to three-quarters of patients of both sexes with the classical salt wasting (SW) form. Non classical patients may present as precocious pubarche in children or polycystic ovarian syndrome in young women. 21-OH-D is caused by CYP21 gene mutations which in more than 90% of the cases result from inter-genic recombination between the active CYP21 gene and the inactive CYP21P pseudogene. The degree to which each mutation impairs enzymatic activity is strictly correlated with the clinical severity of the disease. Glucocorticoid and mineralcorticoid replacement therapies are the basics of treatment, although alternative strategies of treatment are being developed. Neonatal screening may identify affected children before SW crises develop, reducing mortality of this disease. Prenatal diagnosis and treatment should be performed in families at risk for classical form, underlining them that long term results in dexamethasone treated subjects have however lacking. Long term outcome shows an adult height generally between 1 and 2 standard deviations under the familial target height and a fertility rate only moderately reduced in female more than in male treated patients.

non disponibile pdf 597 kB