Aprile 1998 - Volume XVII - numero 4

Medico e Bambino


Problemi correnti

Iponatremia da trattamento con DDAVP: la desmopressina e l’enuresi notturna

P.P. MOLINARI, A. LAMBERTINI, G. GIOVANNINI, C. MAGNANI, G. AMBROSIONI

Unità Operativa di Pediatria, Ospedale Maggiore “C.A. Pizzardi”, Bologna

HYPONATREMIA AND SEIZURES FOLLOWING THE ADMINISTRATION OF DDAVP FOR NOCTURNAL ENURESIS

Key words: Desmopressin (DDAVP), Hyponatremia, Seizures, Nocturnal Enuresis

Desmopressin (DDAVP) is widely used in the treatment of primary nocturnal enuresis. It is a safe and effectiv drug, but occasionally water intoxication may occur. We report a 5 - year - old girl who developed generalized seizures due to hyponatremia, after a single therapeutic dose of intranasal DDAVP for enuresis. Guidelines are given to avoid the risk of water intoxication following the DDAVP administration: to exclude from treatment very young children, to control water intake before bed time and to control weight at morning time.

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P.P. Molinari, A. Lambertini, G. Giovannini e coll. Iponatremia da trattamento con DDAVP: la desmopressina e l’enuresi notturna. Medico e Bambino 1998;17(4):227 https://www.medicoebambino.com/?id=9804_227.pdf


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