A 4-year-old girl has been hospitalized with abdominal
pain and weight and height loss. The patient presented
with dysmorphic features and an unusual congenital cardiopathy
that had been diagnosed with Noonan syndrome. Lab
tests, which were positive for anti-tTg antibodies and anti-endomysium,
suggest a second diagnosis: the association of
Noonan syndrome with celiac disease, both potentially responsible
for the late growth. Actually, the exclusion of gluten
from the diet will help to improve her growth and to eliminate
the abdominal pain.
There is, actually, another diagnosis of hypertrophic cardiopathy:
the association with celiac disease has been described
in this case as well. It is possible that the association
with the celiac disease is due to the fact that a patient with
Noonan syndrome is more susceptible to celiac disease.
Vuoi citare questo contributo?
L'accesso è riservato agli abbonati
alla rivista che si siano registrati.
Per accedere all'articolo in formato full text è necessario inserire nella casella di login username e password.
L'immissione di nuovi contenuti è riservata ai soli utenti registrati