REPORT ON A FAMILY WITH PEUTZ-JEGHERS SYNDROME: THE IMPORTANCE OF INSTRUMENTAL SCREENING IN NON SYMPTOMATIC SUBJECT

Key words: Peutz-Jeghers syndrome (PJS), Management

Report on two brothers with PJS and a positive family history. The first one symptomatic from when was 16 months; the second one asymtomatic underwent to EGDS when fifteen and after endoscopic removal of 6 polyps (the biggest >3 cm) develop emorragic shock symtoms. An early application of surveillance programs to non symptomatic subject also is important, especially if a significant family history is present.