Aprile 2001 - Volume XX - numero 4
Focus
Clinica Pediatrica dell’Università di Trieste, IRCCS “Burlo Garofolo”, Trieste
Key words: Recurrent febrile syndromes, Iper-IgD, Mediterranean fever, Cyclic neutropenia, PFAPA (Periodic Fever, Aphtous stomatitis, Pharyngitis and Adenitis)
A literature review is presented covering the recent advances regarding molecular bases and clinical features of recurrent febrile syndromes in childhood. These include hypoimmune (cyclic neutropenia, benign neutropenia) and hyperimmune (mediterranean fever, iper- IgD syndrome, TNFR-associated fever, PFAPA) forms. Cases of cyclic neutropenia, benign neutropenia, mediterranean fever, iper-IgD syndrome and PFAPA are reported.
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