Graves’ disease and thymic hyperplasia: what relationship?
Key words: Thymic hyperplasia, Graves’ disease, Case report
The case of a 10-year-old girl with clinical hypothyroid-ism in substitution treatment is described. After the on-set of symptoms suggestive of mediastinal mass associ-ated with evolution in hyperthyroidism, she was diag-nosed with thymic hyperplasia in Graves’ disease. The mass regressed after antithyroid treatment. Thymic hy-perplasia is a benign condition that can be associated with Graves’ disease even if symptomatic massive en-largement is rare. The pathogenesis is not well under-stood. Antithyroid drugs usually lead to regression, therefore a correct diagnosis by using imaging tech-niques (echography, MRI, and CT), is essential to avoid unnecessary surgical procedures.
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