Rivista di formazione e di aggiornamento professionale del pediatra e del medico di base, realizzata in collaborazione con l'Associazione Culturale Pediatri
M&B Pagine Elettroniche
Corea: malattia reumatica o lupus eritematoso sistemico?
UOS Reumatologia Pediatrica, Clinica Pediatrica De Marchi, IRCCS "Cà Granda" Ospedale Maggiore Policlinico, Milano
Indirizzo per corrispondenza: firstname.lastname@example.org
Chorea: rheumatic fever or systemic lupus erythematosus?
Key words: Chorea, Systemic lupus erythematosus, Rheumatic fever
Chorea is a manifestation of inflammatory involvement of the basal ganglia and caudate nucleus of the central nervous system. A patient with chorea presents with persistent involuntary, purposeless, and usually symmetric movements of the extremities and muscular incoordination. Chorea occurs in approximately 5% of paediatric patients with SLE; it is almost universally associated with the presence of antiphospholipid antibody. Chorea is not considered to be one of the neurological criteria in the diagnosis of SLE; it may be a presentation of SLE or appear in course of the disease. In the case presented, a child with chorea was treated with oral penicillin for the risk of rheumatic fever, even though there was neither a history of streptococcal infection nor were the required diagnostic criteria available. Chorea was a first sign of SLE in the child. It is very important to include SLE in differential diagnosis of chorea, to make timely diagnosis and to begin appropriate therapy.
Vuoi citare questo contributo?