Rivista di formazione e di aggiornamento professionale del pediatra e del medico di base, realizzata in collaborazione con l'Associazione Culturale Pediatri

M&B Pagine Elettroniche

Caso contributivo

Corea: malattia reumatica o lupus eritematoso sistemico?

Federica Cuoco, Marta Torcoletti, Antonella Petaccia, Fabrizia Corona

UOS Reumatologia Pediatrica, Clinica Pediatrica De Marchi, IRCCS "C Granda" Ospedale Maggiore Policlinico, Milano

Indirizzo per corrispondenza: cuoco.federica@gmail.com

Chorea: rheumatic fever or systemic lupus erythematosus?

Key words: Chorea, Systemic lupus erythematosus, Rheumatic fever

Chorea is a manifestation of inflammatory involvement of the basal ganglia and caudate nucleus of the central nervous system. A patient with chorea presents with persistent involuntary, purposeless, and usually symmetric movements of the extremities and muscular incoordination. Chorea occurs in approximately 5% of paediatric patients with SLE; it is almost universally associated with the presence of antiphospholipid antibody. Chorea is not considered to be one of the neurological criteria in the diagnosis of SLE; it may be a presentation of SLE or appear in course of the disease. In the case presented, a child with chorea was treated with oral penicillin for the risk of rheumatic fever, even though there was neither a history of streptococcal infection nor were the required diagnostic criteria available. Chorea was a first sign of SLE in the child. It is very important to include SLE in differential diagnosis of chorea, to make timely diagnosis and to begin appropriate therapy.

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F. Cuoco, M. Torcoletti, A. Petaccia, F. Corona Corea: malattia reumatica o lupus eritematoso sistemico?. Medico e Bambino pagine elettroniche 2014;17(2) https://www.medicoebambino.com/?id=CCO1402_10.html

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