Rivista di formazione e di aggiornamento professionale del pediatra e del medico di base, realizzata in collaborazione con l'Associazione Culturale Pediatri
M&B Pagine Elettroniche
Vitamina D: č indispensabile... ma non esageriamo!
1Scuola di Specializzazione in Pediatria, Universitą di Ferrara
2Clinica Pediatrica, Arcispedale SantAnna, Ferrara
Indirizzo per corrispondenza: firstname.lastname@example.org
Vitamin D is essential...
but do not exaggerate!
Key words: Hypercalcemia, Vitamin D, Nephrocalcinosis
The article presents a case of severe hypercalcemia due to hypervitaminosis D in a 5-month-old infant. The child was fed with infant formula. He received 2 drops of 25-hydroxy vitamin D3/day since he was born. His clinical features showed growth retardation, anorexia and dehydration, axial hypotonia, psychomotor development retardat and closed anterior fontanel. Investigations showed low levels of parathormone, marked hypercalciuria, high levels of 25-OH vitamin D3 and nephrocalcinosis established by ultrasound evaluation. The infant was treated with parenteral hydration, oral prednisone and oral potassium citrate. The Vitamin D supplementation was stopped. Furthermore, the regular feeding milk was replaced with a new low-calcium and vitamin D-free one. This clinical case has to be taken as an example to discourage the routine use of vitamin D metabolites as prophylaxis of hypovitaminosis D.
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