Rivista di formazione e di aggiornamento professionale del pediatra e del medico di base, realizzata in collaborazione con l'Associazione Culturale Pediatri

M&B Pagine Elettroniche

Caso contributivo

Quando il dolore osseo viene… dal sangue

Lorenzo Mambelli1, Lucia Marangio1, Luana Pini2, Iole Augusta Venturi2, Marina Poli3, Onofrio Donzelli4, Federico Marchetti2

1Scuola di Specializzazione in Pediatria, Ferrara
2UOC di Pediatria e Neonatologia, Azienda Ospedaliera di Ravenna
3Pediatria di Libera Scelta, AUSL di Ravenna
4UO di Ortopedia e Traumatologia Pediatrica, Istituto Ortopedico Rizzoli, Bologna

When bone pain comes from… the blood

Key words: Thalasso-drepanocytosis, Mild anaemia, Osteonecrosis, Case report

The paper describes the case of an 8-year-old Moroccan girl who presented with recurrent multi-focal bone pains associated with negative flogosis indexes and standard radiological exams. The magnetic resonance exam of her thighbones showed a multi-focal inflammation; bone biopsy showed that the inflammation was aseptic and secondary to an osteonecrosis caused by vaso-occlusive crisis. After the haemoglobin electrophoresis performed in consideration of the persistent evidence of a mild microcytic anaemia with anisocytosis, the diagnosis was of thalasso-drepanocytosis. Thalasso-drepanocytosis is one of the sickle cell syndromes characterised by heterozygosis associated with thalassemic haemoglobinopathy. It can be clinically similar to homozygote drepanocytosis and therefore it needs the same therapeutic approach and follow-up. The case highlights the importance of thinking about sickle cell crisis, also in absence of important anaemization, when foreign patients coming from world’s endemic areas for thalassemic haemoglobinopathy present with recurrent bone pains.

Vuoi citare questo contributo?

L. Mambelli, L. Marangio, L. Pini, I.A. Venturi, M. Poli, O. Donzelli, F. Marchetti Quando il dolore osseo viene… dal sangue. Medico e Bambino pagine elettroniche 2012;15(10) https://www.medicoebambino.com/?id=CCO1210_10.html

L'accesso è riservato agli abbonati alla rivista che si siano registrati.
Per accedere all'articolo in formato full text è necessario inserire username e password.

Username
Password