Immature bladder is a physiologic condition in infants and toddlers. In the great majority of
cases, nocturnal enuresis is accompanied by signs of immature bladder (urgency, frequency,
day incontinence etc.) during daytime. Treatment with alarm devices are effective
in 70% of cases, while bladder training is successful in 50% of cases and desmopressin
(DDAVP) in 25% of cases. DDAVP is an effective drug, although not free from side effects.
It should be considered as an adjunctive approach to a behavioural strategy for bladder
control, rather than a causal therapy.