Giugno 2020 - Volume XXXIX - numero 6

Medico e Bambino


Aggiornamento

Artrite idiopatica giovanile

Loredana Lepore, Serena Pastore, Andrea Taddio

SS di Reumatologia pediatrica, IRCCS Materno-Infantile “Burlo Garofolo”, Trieste

Indirizzo per corrispondenza: andrea.taddio@burlo.trieste.it

Juvenile idiopathic arthritis: a disease that changed its clinical picture

Key words: Juvenile idiopathic arthritis, Cytokines, Lymphocytic subset, Biologic drugs, Treat-to-target

Juvenile idiopathic arthritis is the most frequent rheumatic disease in childhood. Its diagnosis is still clinical and recently new classification criteria have been proposed. Over the past twenty years, there have been significant improvement in understanding the pathogenetic mechanisms leading to the implementation of targeted therapies. Indeed, the introduction of biological drugs has changed the quality of life of these children, with a rapid control of the disease activity and a reduction in the complications related to the disease and to the use of steroids, which is today very limited. The way of evaluating patients has also changed: joint ultrasound has become a fundamental tool of the daily practice of the paediatric rheumatologists. This article aims to highlight the new discoveries that have changed the management and prognosis of patients affected by juvenile idiopathic arthritis.

Vuoi citare questo contributo?

L. Lepore, S. Pastore, A. Taddio Artrite idiopatica giovanile. Medico e Bambino 2020;39(6):357-364 https://www.medicoebambino.com/?id=2006_357.pdf


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