Aprile 2020 - Volume XXXIX - numero 4

Medico e Bambino


Aggiornamento

Covid-19 e risposta immune

Stefano Volpi1,2, Samuele Naviglio3, Alberto Tommasini3,4

1IRCCS “G. Gaslini”, Genova
2Università di Genova
3IRCCS Materno-Infantile “Burlo Garofolo”, Trieste
4Università di Trieste

Indirizzo per corrispondenza: alberto.tommasini@burlo.trieste.it

Covid-19 and immune response: weak defences and self-harms

Key words: Covid-19, SARS-CoV-2, Immune repertoire, Haemophagocytic lymphohistiocytosis, Cytokine storm, Pneumonia

Covid-19 outbreak is about to reach the peak of infected people in Italy. Huge amount of data is being published on this epidemic in all medical journals, with especial concern on severe cases. Unfortunately, most reports are just descriptive and only a few controlled clinical trials are available to unravel the disease pathology and the best therapeutic option. For this reason, the aim of the present paper is to give an update on what is currently known about the immune response to the SARS-CoV-2 virus, focusing on the possible weakness of adaptive immunity and excesses of inflammation.

Vuoi citare questo contributo?

S. Volpi, S. Naviglio, A. Tommasini Covid-19 e risposta immune. Medico e Bambino 2020;39(4):223-231 https://www.medicoebambino.com/?id=2004_223.pdf


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