Dicembre 2019 - Volume XXXVIII - numero 10

Medico e Bambino


Farmacoriflessioni

Soluzioni ipertoniche in aerosol? Anche no, grazie

Luciano Anfossi1, Roberta Calzedda2

1Dipartimento di Pediatria, Ospedale Infantile “Regina Margherita”, Città della Salute e della Scienza di Torino
2Scuola di Specializzazione in Pediatria, Università di Torino

Indirizzo per corrispondenza: roberta.calzedda@gmail.com

Nebulised hypertonic saline? Maybe not, thanks

Key words: Nebulised hypertonic saline, bronchiolitis, acute viral wheezing, inhaled mucolytics

Nebulised hypertonic saline (HS) - usually 3% - has become part of paediatric practice for the management of respiratory diseases such as bronchiolitis and preschool wheezing. Acute bronchiolitis is a common disorder in infancy and often results in hospitalisation. No therapy has been shown to influence the course of the disease, other than supportive care. The quality of evidence of studies on positive effects of 3% nebulised saline is low to moderate and new analyses show no benefit. Prospective blinded studies concerning HS use in preschool children with acute viral wheezing are limited. Moreover, HS can induce bronchonconstriction and worsening of cough and should be used with caution especially in patients with bronchial hyperresponsiveness. Other drugs too are used for nebulisation (i.e. mucolytics) despite their unknown physical properties. The hypertonicity-induced bronchospasm can be prevented with the concurrent use of salbutamol.

Vuoi citare questo contributo?

L. Anfossi, R. Calzedda Soluzioni ipertoniche in aerosol? Anche no, grazie. Medico e Bambino 2019;38(10):634-638 https://www.medicoebambino.com/?id=1910_634.pdf


L'accesso è riservato agli abbonati alla rivista che si siano registrati.
Per accedere all'articolo in formato full text è necessario inserire username e password.

Username
Password




L'immissione di nuovi contenuti è riservata ai soli utenti registrati