Bleeding and thrombosis in systemic lupus erythematosus: two sides of the same coin

Key words: Immune thrombocytopenia, Thrombosis, Antiphospholipid antibody, Systemic lupus erythematosus, Lupus eritematoso sistemico

Systemic lupus erythematosus (SLE) is an inflammatory disease with autoimmune pathogenesis and chronic-relapsing course characterised by a wide and heterogeneous spectrum of manifestations and sometimes opposed coexisting clinical features. The paper reports the case of a young girl with immune thrombocytopenic purpura and antiphospholipid antibody syndrome and describes the complexity of therapeutic management linked to the risk of bleeding and thrombosis.