Ischemic stroke in pediatric age: a shared management starting from the 2017 NICE guidelines

Key words: Ischemic stroke, Neurological deficit, Newborns

Ischemic stroke is a clinical syndrome characterised by the sudden onset of a neurological deficit that can refer to the perfusion area of a cerebral artery and by the neuroradiologic evidence of an ischemic lesion. The incidence of ischemic stroke in paediatric age, excluding the neonatal one, is 1-6/100,000 children per year. The incidence is higher in newborns (25-50/100,000 newborns) and it is even higher in premature newborns (100/100,000 newborns). Morbidity is still high, mortality ranges between 5% and 28%. Recurrence risk is about 20-30%. The goal of the this paper is to discuss, starting from the description of a case of ischemic stroke, the present evidence and recommendations on its management considering the recent NICE (The National Institute for Health and Care Excellence) guidelines that bring about some novelties.