1Terapia Intensiva Neonatale, Azienda Ospedaliero-Universitaria, Policlinico, Modena
2Unità per le Malattie Batteriche Sistemiche e Respiratorie, Dipartimento MIPI, Istituto Superiore di Sanità, Roma
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Key words: Group B Streptococcus, Sepsis, Newborn infant, Prophylaxis
The management of neonates at risk of early-onset sepsis is a challenge. In the last years, the approach has been based on laboratory tests that have been proven to be low predictive. Recent Italian data suggest that a less invasive approach, based on careful physical examination, may replace testing. Starting from 2009 in Emilia Romagna (Italy) asymptomatic neonates at risk of early-onset sepsis do not undergo sepsis workup. Clinicians and nurses in turn fill in and sign a standardized form (detailing general wellbeing, skin colour including perfusion, and the presence of respiratory signs) at close intervals. At-risk neonates are diagnosed in a timely manner through this strategy.
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