Aprile 2011 - Volume XXX - numero 4
Clinica Pediatrica, IRCCS “Burlo Garofolo”, Trieste
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Key words: Vasculitides, Childhood, Takayasu arteritis, Wegener granulomatosis, Churg-Strauss syndrome, Cutaneous polyarteritis
The most common vasculitides in children are Schönlein-Henoch purpura and Kawasaki disease, both of which are usually easy to diagnose and treat and have a good prognosis. Nevertheless, the typical adult vasculitides, such as Takayasu arteritis, Wegener granulomatosis, Churg-Strauss syndrome and cutaneous polyarteritis can also occur in childhood. Because of the very low incidence of these conditions in children, suspecting them is difficult and diagnostic delay is frequent. This can lead to severe organ damage often associated with a poor prognosis. Some simple suggestions applied to the daily clinical practice can be helpful in recognizing these conditions and making an early diagnosis in order to begin a prompt therapy. Despite this, the treatment of these vasculitides is difficult and complete remission is not always achieved although it usually improves the long term prognosis.
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