Gennaio 2008 - Volume XXVII - numero 1

Medico e Bambino


Farmacoriflessioni

Il racecadotril

MASSIMO FONTANA

Struttura Complessa di Pediatria, Ospedale dei Bambini “V. Buzzi”, Milano

Indirizzo per corrispondenza: fontana@unimi.it

DRUG THERAPY OF ACUTE DIARRHEA: RACECADOTRIL

Key words: Racecadotril, Acute diarrhea, Intestinal secretion, Stool output

Racecadotril, through the competitive inhibition of enkephalinase, increases the activity of endogenous enkephalines and reduces the intestinal secretion in vitro and in animal models. Clinical trials showed its efficacy in acute diarrhea of adults and children. The most relevant finding is its ability to rapidly reduce the stool output. In this paper are briefly discussed the clinical indications and the safety profile of the drug.

Vuoi citare questo contributo?

M. Fontana. Il racecadotril. Medico e Bambino 2008;27(1):43-46 https://www.medicoebambino.com/?id=0801_43.pdf


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