Aprile 2006 - Volume XXV - numero 4
Farmacoriflessioni
1Dipartimento di Scienze Biomediche, Università di Trieste
2Clinica Pediatrica, Dipartimento di Scienze della Riproduzione e dello Sviluppo, IRCCS “Burlo Garofolo”, Università di Trieste
3Pediatra di famiglia, Pordenone
Indirizzo per corrispondenza: a_saccari@libero.it
Key words: Steroids, Resistance, Hypersensitivity, Molecular mechanisms
Steroids are among the drugs of most common use in paediatric practice. This widespread use does not usually correspond to a thorough knowledge of the mechanisms underlying steroid pharmacology, especially of the steroid resistance and hypersensitivity. This paper reviews the molecular mechanisms underlying steroid resistance and hypersensitivity and reports a few related clinical cases which may be encountered in the every day clinical practice.
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