Settembre 2005 - Volume XXIV - numero 7

Medico e Bambino


Problemi correnti

Helicobacter pylori tra “Nelson” ed EBM

ANNALISA CACCIOLA1, CRISTINA COCUCCIO1, ELEONORA DI TOMMASO1, SIMONA FARACI2, GIUSEPPE LIOTTA3, ANTONIO MUSOLINO1, GIUSEPPE PAGANO4, GIUSEPPE VIENI1

1Specializzandi in Pediatria, Università di Messina
2Medico Laureato presso l’Università di Messina
3Specializzando in Pediatria, Università di Palermo
4Specialista in Pediatria, Università di Messina

Indirizzo per corrispondenza: giuseppevieni@libero.it

HELICOBACTER PYLORI: BETWEEN “NELSON TEXTBOOK” AND EVIDENCE-BASED MEDICINE

Key words: Helicobacter pylori, Eradication, Evidence-based medicine

The Authors describe a clinical case which leads to 4 questions: a) Can Helicobacter pylori (Hp) cause acute abdominal pain? b) If yes, which is the most accurate test to identify Hp? c) If Hp is isolated, should it be eradicated? d) What is the evidence based therapy in order to eradicate Hp? The Authors try to answer these 4 questions both by checking an updated edition of a Pediatrics textbook and the Cochrane Library and by critically analysing the primary literature published on PubMed. They conclude that Hp can cause acute abdominal pain but only when it causes a gastric ulcer. The most accurate test is the fecal antigen test. Hp eradication should be pursued only when gastric ulcer is present, using the association of 2 antibiotics and omeprazole.

Vuoi citare questo contributo?

A. Cacciola, C. Cocuccio, E. Di Tommaso, et al. Helicobacter pylori tra “Nelson” ed EBM. Medico e Bambino 2005;24(7):457 https://www.medicoebambino.com/?id=0507_457.pdf


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