Marzo 2005 - Volume XXIV - numero 3

Medico e Bambino


Farmacoriflessioni

Antileucotrieni nel bambino con “viral wheezing” ricorrente

ATTILIO BONER1, GIORGIO LONGO2, STEFANO MICELI SOPO3

1Clinica Pediatrica, Policlinico “G.B. Rossi”, Università di Verona
2Clinica Pediatrica, IRCCS “Burlo Garofolo”, Trieste
3Dipartimento di Scienze Pediatriche, Università Cattolica del Sacro Cuore, Roma

Indirizzo per corrispondenza: longog@burlo.trieste.it

THE USE OF ANTILEUKOTRIENES IN CHILDREN WITH RECURRENT VIRAL WHEEZING

Key words: Antileukotrienes, Preventive treatment, Wheezing, Asthma

In children with frequent wheezing, frequent and serious episodes of asthmatic dispnoea and risk factors for asthma and atopia, low-dose inhaled steroids should be used as preventive treatment since bronchial inflammation is primarily due to eosinophils. In children with the same characteristics but with no risk factors for asthma and atopia, bronchial inflammation is mostly sustained by neutrophils and their mucus is rich of leukotrienes, hence suggesting the use of montelukast. It is reasonable to reserve any preventive treatment only to those children with a frequent recurrence of acute and clinically important episodes.

Vuoi citare questo contributo?

A. Boner, G. Longo, S. Miceli Sopo
Antileucotrieni nel bambino con “viral wheezing” ricorrente
Medico e Bambino 2005;24(3):171-173 https://www.medicoebambino.com/?id=0503_171.pdf


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