As a rule bollous impetigo is caused by Staphylococcus aureus. Non bullous, or contagious,
impetigo is also caused by Staphylococcus aureus, less frequently by its association with
Streptococcus pyogenes. Controlled studies showed that topical antibiotics such as mupirocine
and fusidic acid are at least as effective as oral antibiotics. Oral antibiotics remain the treatment
of choice in case of familial cases, of perioral localisation and of systemic involvement.
In these cases, although controlled studies are not available, 1st and 2nd generation cephalosporins,
amoxicillin-clavulanic and macrolides are recommended.