Aprile 2002 - Volume XXI - numero 4
Controversie
1Clinica Pediatrica, IRCCS “Burlo Garofolo”, Trieste,Dipartimento di Pediatria, Azienda Sanitaria di Modena
Key words: Bronchiolitis, Oxygen, Rehydration, Adrenaline
With regard to bronchiolitis, strong evidence of effectiveness does exist only for oxygen and
hydration. There is some evidence on the effectiveness of nebulised adrenaline, but it does not
significantly improve the clinical course, nor reduce the need for intensive care. There is no
sufficient evidence with respect to its possible use at home, also taking into account the uncertainties
on its safety profile.
The literature available on bronchiolitis shows that the effects of steroids, beta2-agonists and
adrenaline are modest. However, there are patients who do respond to treatment and since
we are not able to identify these patients, a treatment trial may be worthy. Recent evidence
shows that effects of salbutamol and steroids may be synergic and that they are greater as the
child gets older.
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