Aprile 2001 - Volume XX - numero 4

Medico e Bambino


Focus

FEBBRI PERIODICHE
Sindromi febbrili periodiche in Pediatria

ALBERTO TOMMASINI, ELENA NERI

Clinica Pediatrica dell’Università di Trieste, IRCCS “Burlo Garofolo”, Trieste

RECURRENT FEBRILE SYNDROMES IN CHILDHOOD

Key words: Recurrent febrile syndromes, Iper-IgD, Mediterranean fever, Cyclic neutropenia, PFAPA (Periodic Fever, Aphtous stomatitis, Pharyngitis and Adenitis)

A literature review is presented covering the recent advances regarding molecular bases and clinical features of recurrent febrile syndromes in childhood. These include hypoimmune (cyclic neutropenia, benign neutropenia) and hyperimmune (mediterranean fever, iper- IgD syndrome, TNFR-associated fever, PFAPA) forms. Cases of cyclic neutropenia, benign neutropenia, mediterranean fever, iper-IgD syndrome and PFAPA are reported.

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A. Tommasini, E. Neri
FEBBRI PERIODICHE; Sindromi febbrili periodiche in Pediatria
Medico e Bambino 2001;20(4):225-238 https://www.medicoebambino.com/?id=0104_225.pdf

Focus

La tonsillite ricorrente e la tonsillite focale: una rivisitazione

PIERLANFRANCO D’AGARO, FRANCO PANIZON, ALESSANDRO VENTURA, ELISABETTA ZOCCONI

Istituto di Igiene, Clinica Pediatrica, UO di ORL Pediatrica, IRCCS “Burlo Garofolo”, Trieste

FOCAL AND RECURRENT PHARYNGITIS: A REVIEW

Key words: Recurrent pharyngitis, Adenovirus, FPAPA (Periodic Fever, Aphtous stomatitis, Pharyngitis and Adenitis)

20 cases of recurrent pharyngitis, among whom 9 have undergone tonsillectomy, are compared with 9 cases of tonsillar hypertrophy, all of whom had undergone surgery. Adenovirus etiology was confirmed in 8 out of 14 cases belonging to the first group in whom appropriate laboratory examinations could be performed, and in 1 out of 9 cases of the second group. Based on these findings and on a literature review an auto-inflammatory hypothesis of recurrent pharyngitis is proposed. Adenovirus, and EBV in older children could be the sensitising agent. The Authors suggest that recurrent pharyngitis, when criteria of cyclicity, abnormality of inflammatory markers and intercritical normality are satisfied, may not be differentiated from FPAPA syndrome.

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P. D’Agaro, F. Panizon, A. Ventura, E. Zocconi
La tonsillite ricorrente e la tonsillite focale: una rivisitazione
Medico e Bambino 2001;20(4):231-238 https://www.medicoebambino.com/?id=0104_225.pdf

Focus

Incidenza e storia naturale della PFAPA in Friuli-Venezia Giulia: una ricerca collaborativa dei PdF

GIANCARLO BESOLI E GRUPPO DI STUDIO SULLA PFAPA DEL FRIULI-VENEZIA GIULIA; Egidio Barbi1, Giancarlo Besoli, Laura Brusadin, Gabriella Cescato, Magda di Comun, Piero Iaschi, Lorena Loschi, Carmen Mazzolini, Giorgio Mussi, Marilena Pavoni, Mariagrazia Pizzul, Alda Predotto, Francesco Romanello, Daniele Rosenwirth, Raffaella Servello, Angelo Tarchino, Lidia Tion, Antonella Ulliana, Alessandro Ventura1, Oscar Volpi

1Clinica Pediatrica, IRCCS “Burlo Garofolo”, Trieste

INCIDENCE AND NATURAL HISTORY OF FPAPA IN FRIULI-VENEZIA GIULIA: A COLLABORATIVE STUDY BY FAMILY PAEDIATRICIANS

Key words: Recurrent pharyngitis, FPAPA (Periodic Fever, Aphtous stomatitis, Pharyngitis and Adenitis)

Through a review of all cases seen during the last 5 years, 20 practicing paediatricians were able to identify 40 cases who satisfy the diagnostic criteria for FPAPA. Recurrence range was between 3 and 6 weeks and overall duration from 1 to 6 years. 12 cases were successfully treated with a single dose of steroids, 12 underwent surgery and were all cured, 1 was treated with inhalatory steroids and recovered. The remaining 12 recovered spontaneously.

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G. Besoli e Gruppo di Studio sulla Pfapa Del Friuli-Venezia Giulia
Incidenza e storia naturale della PFAPA in Friuli-Venezia Giulia: una ricerca collaborativa dei PdF
Medico e Bambino 2001;20(4):234-238 https://www.medicoebambino.com/?id=0104_225.pdf


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