1Terapia Intensiva Neonatale (TIN), Azienda Policlinico, Modena; 2Scuola di Specializzazione in Pediatria, Università di Modena e Reggio Emilia; 3TIN, Ospedale Maggiore, Bologna; 4TIN, Azienda Policlinico Sant’Orsola - Malpighi, Bologna; 5TIN, Ospedale Infermi, Rimini; 6TIN, Arcispedale Santa Maria Nuova, Reggio Emilia; 7TIN, Azienda Policlinico, Parma; 8TIN, Arcispedale Sant’Anna, Ferrara; 9TIN, Ospedale Bufalini, Cesena; 10TIN, Ospedale Santa Maria Delle Croci, Ravenna
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Key words: Group B streptococcus, Sepsis, Newborn infant, Prophylaxis
The approach to the newborn at risk of early-onset sepsis is a challenge. In the past the approach was mainly based on laboratory tests, which were poorly predictive and might cause repeated blood samples and unnecessary antibiotic therapies, with possible long-term side effects. The medicalisation of asymptomatic newborns also interferes with breastfeeding. Recent experiences carried out in the Friuli Venezia Giulia and Emilia-Romagna Regions (Italy) have suggested that a less invasive approach is useful. This approach is mainly based on careful and repeated clinical observations of asymptomatic full-term or late preterm infants at standard intervals, regardless of risk factors. Moreover, it is useful for a timely diagnosis, does not separate mothers from their neonates and consequently does not interfere with the development of the nascent intestinal microbiota and breastfeeding.
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