Marzo 2007 - Volume XXVI - numero 3

Medico e Bambino


Farmacoriflessioni

Vaccini anti-rotavirus. quale? quando? perché? per chi?

M. Fontana

Indirizzo per corrispondenza: massimo.fontana@unimi.it

ROTAVIRUS VACCINES

Key words: Vaccino anti-rotavirus

Two new Rotavirus vaccines are being dispensed soon in Italy. They differ strongly in composition and suggested schedule. Available studies do not allow direct comparisons (severity scales for gastroenteritis are different, as are the cut-off points). Safety for the first dose to be administered beyond the age of three months has not yet proved, so “catch-up” vaccination should be discouraged. Other relevant points which still need definite answers are the possible interaction with oral poliovirus vaccine (especially relevant in developing countries) and the recently suggested role of Rotavirus in the pathogenesis of celiac disease. Moreover, when performing cost-efficacy analysis about Rotavirus vaccination, one should bore in mind the still high number of inappropriate hospital admission for acute gastroenteritis in Italy.

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M. Fontana
Vaccini anti-rotavirus. quale? quando? perché? per chi?
Medico e Bambino 2007;26(3):173-175 https://www.medicoebambino.com/_rotavirus_vaccini_prima_invaginazione_rotateq_diarrea


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