Medico e Bambino
2007
Aprile 2007
numero 4
FARMACORIFLESSIONI










La terapia del croup

F. Marchetti, P. Salierno

indirizzo per corrispondenza:marchetti@burlo.trieste.it

THE TREATMENT OF CROUP
Key words
Croup, Treatment, Randomised controlled trials, Glucocorticoids, Adrenaline,

Summary
Viral croup is the most common cause of upper airway obstruction in children from 6 months to 6 years of age. Parainfluenza virus accounts for the majority of cases. More than 80% of children have mild symptoms and in approximately 60% to 95% of children, the symptoms disappear within 2 and 5 days, respectively. Based on the results of systematic review, glucocorticoid treatment was associated with an improvement in the Westley score at 6 hours and at 12 hours. Fewer return visits and/or (re)admissions occurred in patients treated with glucocorticoids (relative risk 0.50; 0.36 to 0.70). The setting, severity of croup, route of administration (oral or nebulised) and dose, and study quality, did not influence the effectiveness of treatment. Nebulised adrenaline should be reserved for patients with moderate to severe croup. Simultaneous administration of glucocorticoid and adrenaline reduces the rate of intubation in patients with severe croup. Mist/humidified air provides no additional symptom improvement.

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Vuoi citare questo contributo?
F. Marchetti, P. Salierno. LA TERAPIA DEL CROUP. Medico e Bambino 2007;26:242-248 https://www.medicoebambino.com/_croup_desametasone_glucocrticoidi_adrenalina

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