Evidence of the paediatric use of anti-emetics drugs:
the history of domperidone
Key words: Domperidone, Italian Medicines Agency, Anti-emetics
On 2nd May 2019 the Italian Medicines Agency (AIFA) issued an “Informative Note
agreed upon with the European Regulatory Authorities” on domperidone entitled Memorandum
on recommendations for minimising heart risks and eliminating prescriptions in
Paediatrics. The note was drafted in collaboration with the authorised pharmaceutical
companies that produce this drug. The present article reports the full note (because of its
informative nature) and comments its case that has been lasting for many years making
physicians think about the use of anti-emetics in Paediatrics both from a methodological
and practical perspective.
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