Gennaio 2019 - Volume XXXVIII - numero 1
Problemi speciali
1Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università di Trieste
2IRCCS Materno-Infantile “Burlo Garofolo”, Trieste
Indirizzo per corrispondenza: michele.mazzolai90@gmail.com
Key words: Hidradenitis suppurativa, Autoinflammatory disease, Children, Diagnosis, Treatment
Hidradenitis suppurativa (HS) is a chronic and recurrent skin disease affecting apocrine gland-bearing regions. Typical lesions are nodules and abscesses that result in sinus tracts, fistulas and eventually scarring. Prepubertal onset of HS is quite rare, representing only 2% of all HS cases, which are frequently expression of genetic forms, hormonal imbalances or systemic autoinflammatory diseases. Therapy is severity-tailored ranging from topical antibiotics to monoclonal antibodies, saving surgery for unresponsive cases. Early diagnosis and prompt treatment are fundamental to arrest disease progression to milder stages, giving children the opportunity to keep a good quality of life without getting stuck on this condition.
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