Marzo 2016 - Volume XXXV - numero 3

Medico e Bambino


Pagine elettroniche

Chetoacidosi secondaria a tireotossicosi in ragazza con diabete tipo 1 e celiachia

Vanna Graziani1, Andrea Zucchini2, Tosca Suprani3, Francesca Currò1, Lorenzo Mambelli1, Federico Marchetti1

1UOC di Pediatria e Neonatologia, Ospedale di Ravenna; 2Ospedale di Faenza; 3UOC di Pediatria e Neonatologia, Ospedale di Cesena, AUSL della Romagna

Indirizzo per corrispondenza: vanna.graziani@gmail.com

Type 1 diabetes mellitus and coeliac disease with secondary ketoacidosis triggered by thyrotoxicosis: a case report

Key words: Coeliac disease, Diabetes, Ketoacidosis, Thyrotoxicosis

The paper describes the case of a teenager affected by type 1 diabetes mellitus and coeliac disease who presented secondary ketoacidosis (DKA) triggered by thyrotoxicosis. She was successfully treated with beta-blocker and methimazole, in addition to intravenous insulin therapy. The association of thyrotoxicosis and DKA is uncommon but anecdotal cases are reported in literature. Through different mechanisms hyperthyroidism may cause decreased levels of insulin and increased glycogenolysis, ketogenesis, dehydration, and insulin resistance. The possibility of DKA triggered by thyrotoxicosis should be kept in mind in female patient or in the presence of symptoms of hyperthyroidism.

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V. Graziani, A. Zucchini, T. Suprani, F. Currò, L. Mambelli, F. Marchetti Chetoacidosi secondaria a tireotossicosi in ragazza con diabete tipo 1 e celiachia . Medico e Bambino 2016;35(3):191 https://www.medicoebambino.com/?id=1603_191.pdf

Pagine elettroniche

Quando i bambini con l’acetone hanno lingua blu e abbronzatura fuori stagione

Emanuele Castagno1, Irene Tardivo1, Giulia Grasso1, Patrizia Matarazzo2, Gerdi Tuli2, Antonio Francesco Urbino1

1SC di Pediatria d’Urgenza, 2SSVD di Endocrinologia e Diabetologia Pediatrica, AOU Città della Salute e della Scienza di Torino, Ospedale Infantile Regina Margherita, Torino

Indirizzo per corrispondenza: ecastagno@cittadellasalute.to.it

Off-season tan and blue tongue in children with ketosis

Key words: Addison’s disease, Primary adrenocortical failure, Hyperpigmentation, Hyponatraemia, Hypoglycaemia, Ketosis

Addison’s disease (primary adrenocortical failure) is a rare condition mainly of autoimmune origin. Signs and symptoms are usually mild and non-specific, as abdominal pain, failure to thrive, weight loss, anorexia, vomiting and diarrhoea associated to bronzed skin colour. The diagnosis is often delayed. The paper reports two cases of children in which the association between hyperpigmentation and dehydration with metabolic acidosis, hyponatraemia and hypoglycaemia not proportionate to concomitant vomiting led to the clinical suspect.

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E. Castagno, I. Tardivo, G. Grasso, P. Matarazzo, G. Tuli, A.F. Urbino Quando i bambini con l’acetone hanno lingua blu e abbronzatura fuori stagione . Medico e Bambino 2016;35(3):191 https://www.medicoebambino.com/?id=1603_191.pdf


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