Giugno 2008 - Volume XXVII - numero 6
Focus
Paediatric Research Centre, Tampere University Hospital, Tampere, Finlandia
Key words: Coeliac disease, Tissue transglutaminase, Rapid test
Coeliac disease is an autoimmune enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. The diagnosis is suspected upon the presence of typical autoantibodies in the serum of patients, and confirmed by intestinal biopsy. For a long time, these serologic tests were only performable in laboratories. The availability of a rapid test, that can be performed on a large scale, in any setting has significantly simplified the diagnosis of coeliac disease. The Authors of the article explain the way the test functions, the clinical implications and the literature that proved the test as an effective addition to the previously available diagnostic tools for the diagnosis of coeliac disease.
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