Febbraio 2007 - Volume XXVI - numero 2

Medico e Bambino


Focus

È utile l’urokinasi intrapleurica nel trattamento dell’empiema? Una risposta da una esperienza concreta

LETIZIA BOGDANOVITS, EGIDIO BARBI, FEDERICO MARCHETTI, NAGUA GIURICI, LUCA RONFANI, ALESSANDRO VENTURA

Clinica Pediatrica, IRCCS “Burlo Garofolo”, Trieste

Indirizzo per corrispondenza: ebarbi@libero.it

IS INTRAPLEURAL UROKINASE EFFECTIVE IN THE TREATMENT OF EMPYEMA?

Key words: Pleuric empyema, Urokinase

The use of intrapleural fibrynolisis in the treatment of empyema shortens hospital stay and is recommended by international guidelines in children with a B grade of evidence. Even though only few randomized studies have addressed this issue in limited series of patients with conflicting results. One trial for urokinase showed a positive result while another trial with streptokinase did not show a significant reduction in length of hospital stay. We retrospectively rewied a 30 year experience in a third level university hospital comparing length of treatment in a group of children treated with simple drainage and a group treated with urokinase. Even if such a retrospective analysis is limited by possible biases which are highlighted and discussed a significant reduction in length of hospital stay was found without side effects.

Vuoi citare questo contributo?

L. Bogdanovits, E. Barbi, F. Marchetti, N. Giurici, L. Ronfani, A. Ventura
È utile l’urokinasi intrapleurica nel trattamento dell’empiema? Una risposta da una esperienza concreta
Medico e Bambino 2007;26(2):89-102 https://www.medicoebambino.com/?id=0702_089.pdf


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