Settembre 2005 - Volume XXIV - numero 7
Focus
Dipartimento di II Patologia Chirurgica, Spedali Civili, Brescia
Key words: Duodenal biopsy, Intraepithelial lymphocytes
When diagnosing celiac disease, the intestinal biopsy represents a moment of close collaboration between the pathologist and the clinician. The accuracy of the hystological diagnosis depends on the number and the adequate placement of the biopsies on the slides. It is fundamental to correctly interpret the biopsy in order to recognise artefacts and to describe the different mucosal strata, the relation between villus/crypt and the presence of intraepithelial lymphocytes. All these characteristics are of great help for the clinician in order to identify non clear celiac forms.
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