TREMORS AND CHOREA DUE TO HIGH DOSES OF TRIMETHOPRIM-SULFAMETHOXAZOLE IN A CHILD WITH PNEUMOCYSTIS CARINII PNEUMONIA

Key words: Trimethoprim-sulfamethoxazole, Adverse effects, Tremors, Chorea, Pneumonia

The Authors describe a case of a child with interstitial lung disease caused by Pneumocystis carinii pneumonia who developed tremors and choreic movements after treatment with high doses of trimethoprim-sulfamethoxazole. The patient developed immune deficiency due to prolonged immunosuppressive therapy. The tremors disappeared 3 days after the drug was discontinued. Paediatricians should be aware of the possible occurrence of tremors and choreic movements among children who are receiving high doses of TMP/SMX.