Novembre 2001 - Volume XX - numero 9

Medico e Bambino


Farmacologia clinica

Gli antistaminici in Dermatologia pediatrica

ERNESTO BONIFAZI

Dermatologia Pediatrica, Bari

ANTIHISTAMINES IN PAEDIATRIC DERMATOLOGY

Key words: Antihistamines, Urticaria, Atopic dermatitis, Mastocytosis

The Author offers an overview of the pharmacological properties of first, second, and third generation antihistamines and discusses their indications in paediatric dermatology (urticaria, insect bites, atopic dermatitis and mastocytosis). Loratadine (or cetirizine in the first 2 years of age) is indicated for acute urticaria. Severe and acute cases should be treated with parenteral clorpheniramine and prednisone. Acrivastine can be used for prevention of urticaria when exposure to the trigger is inevitable. When insect bites are recent and particularly numerous a second generation antihistamine should be used. The same class of drugs is indicated in mastocytosis. Atopic dermatitis does not respond well to antihistamines and the use should be confined to treating severe pruritus, particularly at night time. Antihistamines should not be used to treat pruritus in herpetic dermatitis, scabies or lice, where etiologic treatment must be prioritised.

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E. Bonifazi Gli antistaminici in Dermatologia pediatrica. Medico e Bambino 2001;20(9):604 https://www.medicoebambino.com/?id=0109_601.pdf


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